Infected pressure ulcers, mental capacity act and deprivation of liberties - Jeanette Milne
Many patients with infected wounds consent to treatment this and concordance with treatment regimens can be the key to achieving successful outcomes. This presentation will focus on care priorities when managing patients with infected pressure ulcers when the mental capacity act (MCA) and deprivation of liberties (DOL) standards have to be applied. In addition, it will explore how legislation can be used to help improve patient outcomes.
• Delegates will be able to recognise when patients need to have a MCA
Lympho-epithelial interactions in responses: the importance of cellular state, cell proliferation related signalling and the involvement of microbial infection-associated molecular patterns in the process of wound healing - Dr Nikolaos Georgopoulos
Wound healing can be described as an immuno-epithelial ‘symphony’ that involves well-orchestrated cell migration/proliferation, inflammation, innervation and angiogenesis. The process of successful wound healing is associated with the spatial and temporal involvement of different cell types, where the type of interactions and their timing is critical and involves epithelial and mesenchymal cells, as well as immunocytes. Detecting tissue injury and responding by initiating repair is vital for survival but, interestingly, epithelial tissues have evolved to utilise infection associated “molecular patterns” (danger signals) as an important signalling factor (trigger) in the wound healing process. The presentation will provide an overview of these processes and will relate to our recent laboratory studies that have permitted a better understanding of what molecular mediators are released during successful wound healing responses.
When should I stop antimicrobial treatment? - Professor Valerie Edwards-Jones
Changing the spectrum of surgical site infection assessment: from visual to the infra-red - Professor Charmaine Childs
Looking at wounds, with the objective of making an assessment of healing progress is tried and tested over centuries. When wounds break down, there are a number of ways that clinicians can summarise the visual appearance of the wound; scoring systems being the most common. Could we do more?
In this lecture, we will be looking beyond the visual spectrum and into the infrared. Our research shows that thermography provides an additional assessment option with the wound ''thermal signature'' providing new ways to stratify patients ''at risk '' of surgical site infection (SSI).
Linking research to practice: case studies - Leanne Atkin
Wound healing is a complex, multifaceted process influenced by intrinsic and extrinsic factors, some of which can be controlled. When healing stalls and certain signs and symptoms are present, the wound may be critically colonised or infected. There is no single scientific test to definitively diagnose infection; wound infection is diagnosed by clinical assessment of the wound and the whole patient. It is therefore important that clinicians understand how infection develops, how signs and symptoms manifest in various aetiologies, and how and when to initiate use of topical antimicrobials and systemic antibiotics in wounds clinically diagnosed as infected.
Linking research to practice: case studies - Dr Jess Power
The project undertakes innovative experimental and industrial research contributing to the design of a child focused “Wiggle Bag” which will be used to safely harness and reduce infection at the site of a catheter tail in the chest of long-term child cancer sufferers. Children with cancer regularly have long term central line catheters inserted in the chest to deliver medication. Often termed ‘Hickman Lines’, they result in tubing protruding from the chest, which can result in medical issues including infections, but also discomfort for the child, particularly when sleeping. The research uses an inductive approach, triangulating various research strategies including questionnaires, focus groups and interviews from parents, carers and medical personnel. QFD was used to bring together the key findings from the primary data analysis to establish a design criteria and the product development. The outcome of the research was a functional product ergonomically designed for maximum comfort and safety, with the added unique selling point of antibacterial properties.
Wound Infection, accountability and negligence - Keith F Cutting
Patient’s experience of using medical devices following traumatic amputation & Skin deep pressure injury prevention: Protecting deep tissues from sustained deformations - Professor Amit Gefen
Sustained internal mechanical deformations in soft tissues during immobile weight-bearing postures (e.g. in bed or in a chair) were identified as a fundamental cause for the onset and progression of pressure injuries, especially of the deep tissue injury type. The sustained deformations in tissues may compromise tissue viability through distortion of cell shapes
The Importance of Bioengineering in a skin health multidisciplinary team - Professor Dan Bader
A history of wound imaging: where are we today, where should we be tomorrow? - Professor Steve Jeffery
Wounds have been represented pictorially for hundreds of years. Wounds could be measured, and their dimensions could be written down. Wound tracings could also be taken, allowing serial assessment of whether the wound was in fact getting bigger or smaller. The Digital Revolution, the change from analogue and mechanical technology to digital technology, began in the latter half of the last century and continues to the present day. The reduction in cost and the increased availability of digital photography has meant that currently most people own a digital camera, and indeed most people carry around a mobile telephone capable of taking very high resolution images.
As well as measuring the wounds, new cameras are available which can inform us regarding other aspects of the wound, such as bacterial content. In future cameras will be developed which can inform clinicians about aspects of the wound that were previously unimaginable.
Can we exploit the mechanosensitive properties of cells and tissues to aid wound healing? - Dr Mark Murphy
Cells, by their very nature, have evolved to respond to external physical cues through a known as mechanotransduction, whereby physical cues acting on cells and tissues are converted into a biochemical response. Recent work has highlighted the potential of exploiting this mechanosensitivity, both in vivo and in vitro. For example, studies in a clinical setting have shown that applying mechanical stimulation to patients suffering from conditions such as Multiple Sclerosis can improve short term symptoms. Whilst studies using bone progenitor cells has shown mechanical stimulation to be anabolic for bone and it has been suggested mechanical stimulation may prove an effect treatment to treat patients with suffering from conditions associated with a loss of bone mass. Such studies highlight the potential of using mechanical stimulation as a novel therapeutic treatment however to date little has been done in this area, particularly when applied to wound healing.
Pressure ulcer prevention in the seated individual - Professor Zena Moore
• The link between seating and pressure ulcer development